Gene description for CLU
Gene name clusterin
Gene symbol CLU
Other names/aliases -
Species Equus caballus
 Database cross references - CLU
ExoCarta ExoCarta_100034172
Vesiclepedia VP_100034172
Entrez Gene 100034172
UniProt None  
 CLU identified in exosomes derived from the following tissue/cell type
Follicular fluid 22116803    
 Gene ontology annotations for CLU
Molecular Function
    misfolded protein binding GO:0051787 IEA
Biological Process
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IEA
    regulation of apoptotic process GO:0042981 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified CLU in exosomes
1
Experiment ID 147
MISEV standards
EM
Biophysical techniques
HSP70|CD63
Enriched markers
cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22116803    
Organism Equus caballus
Experiment description Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle
Authors da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ
Journal name Biol Reprod
Publication year 2011
Sample Follicular fluid
Sample name Follicular fluid - Ovarian - Young mare
Isolation/purification methods Differential centrifugation
Exoquick
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-PCR
Mass spectrometry [LTQ]
 Protein-protein interactions for CLU
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CLU is involved
No pathways found





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