Gene description for A2M
Gene name alpha-2-macroglobulin
Gene symbol A2M
Other names/aliases -
Species Equus caballus
 Database cross references - A2M
ExoCarta ExoCarta_100061656
Vesiclepedia VP_100061656
Entrez Gene 100061656
UniProt None  
 A2M identified in exosomes derived from the following tissue/cell type
Follicular fluid 22116803    
 Gene ontology annotations for A2M
Molecular Function
    protease binding GO:0002020 IEA
    endopeptidase inhibitor activity GO:0004866 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified A2M in exosomes
1
Experiment ID 147
MISEV standards
EM
Biophysical techniques
HSP70|CD63
Enriched markers
cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22116803    
Organism Equus caballus
Experiment description Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle
Authors da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ
Journal name Biol Reprod
Publication year 2011
Sample Follicular fluid
Sample name Follicular fluid - Ovarian - Young mare
Isolation/purification methods Differential centrifugation
Exoquick
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-PCR
Mass spectrometry [LTQ]
 Protein-protein interactions for A2M
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which A2M is involved
No pathways found





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