Gene description for SPI2
Gene name alpha-1-antitrypsin
Gene symbol SPI2
Other names/aliases -
Species Equus caballus
 Database cross references - SPI2
ExoCarta ExoCarta_100065158
Vesiclepedia VP_100065158
Entrez Gene 100065158
UniProt None  
 SPI2 identified in exosomes derived from the following tissue/cell type
Follicular fluid 22116803    
 Gene ontology annotations for SPI2
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
Biological Process
    negative regulation of endopeptidase activity GO:0010951 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified SPI2 in exosomes
1
Experiment ID 147
MISEV standards
EM
Biophysical techniques
HSP70|CD63
Enriched markers
cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22116803    
Organism Equus caballus
Experiment description Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle
Authors da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ
Journal name Biol Reprod
Publication year 2011
Sample Follicular fluid
Sample name Follicular fluid - Ovarian - Young mare
Isolation/purification methods Differential centrifugation
Exoquick
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-PCR
Mass spectrometry [LTQ]
 Protein-protein interactions for SPI2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPI2 is involved
No pathways found





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