Gene description for FGA
Gene name fibrinogen alpha chain
Gene symbol FGA
Other names/aliases -
Species Equus caballus
 Database cross references - FGA
ExoCarta ExoCarta_100069763
Vesiclepedia VP_100069763
Entrez Gene 100069763
UniProt None  
 FGA identified in exosomes derived from the following tissue/cell type
Follicular fluid 22116803    
 Gene ontology annotations for FGA
Molecular Function
    signaling receptor binding GO:0005102 IEA
    extracellular matrix structural constituent GO:0005201 IEA
Biological Process
    blood coagulation GO:0007596 IEA
    platelet activation GO:0030168 IEA
    positive regulation of heterotypic cell-cell adhesion GO:0034116 IEA
    fibrinolysis GO:0042730 IEA
    protein polymerization GO:0051258 IEA
    positive regulation of ERK1 and ERK2 cascade GO:0070374 IEA
    platelet aggregation GO:0070527 IEA
    blood coagulation, common pathway GO:0072377 IEA
    positive regulation of peptide hormone secretion GO:0090277 IEA
    negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 IEA
    negative regulation of endothelial cell apoptotic process GO:2000352 IEA
Subcellular Localization
    fibrinogen complex GO:0005577 IEA
 Experiment description of studies that identified FGA in exosomes
1
Experiment ID 147
MISEV standards
EM
Biophysical techniques
HSP70|CD63
Enriched markers
cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22116803    
Organism Equus caballus
Experiment description Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle
Authors da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ
Journal name Biol Reprod
Publication year 2011
Sample Follicular fluid
Sample name Follicular fluid - Ovarian - Young mare
Isolation/purification methods Differential centrifugation
Exoquick
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-PCR
Mass spectrometry [LTQ]
 Protein-protein interactions for FGA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FGA is involved
No pathways found





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