Gene description for ITIH2
Gene name inter-alpha-trypsin inhibitor heavy chain 2
Gene symbol ITIH2
Other names/aliases -
Species Equus caballus
 Database cross references - ITIH2
ExoCarta ExoCarta_100070004
Vesiclepedia VP_100070004
Entrez Gene 100070004
UniProt None  
 ITIH2 identified in exosomes derived from the following tissue/cell type
Follicular fluid 22116803    
 Gene ontology annotations for ITIH2
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
Biological Process
    hyaluronan metabolic process GO:0030212 IEA
 Experiment description of studies that identified ITIH2 in exosomes
1
Experiment ID 147
MISEV standards
EM
Biophysical techniques
HSP70|CD63
Enriched markers
cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22116803    
Organism Equus caballus
Experiment description Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle
Authors da Silveira JC, Veeramachaneni DN, Winger QA, Carnevale EM, Bouma GJ
Journal name Biol Reprod
Publication year 2011
Sample Follicular fluid
Sample name Follicular fluid - Ovarian - Young mare
Isolation/purification methods Differential centrifugation
Exoquick
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-PCR
Mass spectrometry [LTQ]
 Protein-protein interactions for ITIH2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITIH2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here