Gene description for LIG1
Gene name ligase I, DNA, ATP-dependent
Gene symbol LIG1
Other names/aliases -
Species Bos taurus
 Database cross references - LIG1
ExoCarta ExoCarta_100124507
Vesiclepedia VP_100124507
Entrez Gene 100124507
 LIG1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LIG1
Molecular Function
    DNA binding GO:0003677 IEA
    DNA ligase (ATP) activity GO:0003910 IEA
    ATP binding GO:0005524 IEA
Biological Process
    lagging strand elongation GO:0006273 IEA
    DNA repair GO:0006281 IEA
    DNA recombination GO:0006310 IEA
    DNA biosynthetic process GO:0071897 IEA
    Okazaki fragment processing involved in mitotic DNA replication GO:1903461 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified LIG1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LIG1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LIG1 is involved
No pathways found





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