Gene description for RAB8A
Gene name RAB8A, member RAS oncogene family
Gene symbol RAB8A
Other names/aliases -
Species Bos taurus
 Database cross references - RAB8A
ExoCarta ExoCarta_100125881
Entrez Gene 100125881
UniProt A4FV54  
 RAB8A identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB8A
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 ISS
    myosin V binding GO:0031489 IEA
    Rab GTPase binding GO:0017137 ISS
    GDP binding GO:0019003 ISS
Biological Process
    cilium assembly GO:0042384 ISS
    intracellular protein transport GO:0006886 IBA
    synaptic vesicle exocytosis GO:0016079 IBA
    vesicle docking involved in exocytosis GO:0006904 IBA
    axonogenesis GO:0007409 ISS
    cellular response to insulin stimulus GO:0032869 ISS
    protein localization to plasma membrane GO:0072659 ISS
    metabolic process GO:0008152 IBA
    regulation of exocytosis GO:0017157 IBA
    protein secretion GO:0009306 IBA
    Rab protein signal transduction GO:0032482 IBA
    Golgi vesicle fusion to target membrane GO:0048210 IBA
Subcellular Localization
    centrosome GO:0005813 IEA
    secretory granule membrane GO:0030667 IBA
    nucleoplasm GO:0005654 IEA
    nonmotile primary cilium GO:0031513 IEA
    synaptic vesicle GO:0008021 IBA
    cilium GO:0005929 ISS
    endosome GO:0005768 IBA
    ciliary basal body GO:0036064 IEA
    extracellular exosome GO:0070062 IEA
    nucleolus GO:0005730 IEA
    plasma membrane GO:0005886 IBA
    phagocytic vesicle membrane GO:0030670 IEA
    phagocytic vesicle GO:0045335 ISS
    trans-Golgi network transport vesicle GO:0030140 IBA
    recycling endosome membrane GO:0055038 ISS
 Experiment description of studies that identified RAB8A in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB8A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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