Gene description for ELANE
Gene name elastase, neutrophil expressed
Gene symbol ELANE
Other names/aliases ELA2
Species Bos taurus
 Database cross references - ELANE
ExoCarta ExoCarta_100126050
Vesiclepedia VP_100126050
Entrez Gene 100126050
 ELANE identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ELANE
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
Biological Process
    acute inflammatory response to antigenic stimulus GO:0002438 IEA
    proteolysis GO:0006508 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified ELANE in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ELANE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ELANE is involved
No pathways found





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