Gene description for Rab1b
Gene name RAB1B, member RAS oncogene family
Gene symbol Rab1b
Other names/aliases Rab1bl
Species Rattus norvegicus
 Database cross references - Rab1b
ExoCarta ExoCarta_100126191
Entrez Gene 100126191
 Rab1b identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Rab1b
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 ISS
Biological Process
    virion assembly GO:0019068 IEA
    positive regulation of glycoprotein metabolic process GO:1903020 IEA
    regulation of autophagosome assembly GO:2000785 IEA
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    autophagy GO:0006914 IEA
    metabolic process GO:0008152 IBA
    intracellular protein transport GO:0006886 IBA
    Rab protein signal transduction GO:0032482 IBA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IEA
    mitochondrion GO:0005739 IEA
    pre-autophagosomal structure membrane GO:0034045 IEA
    Golgi membrane GO:0000139 IBA
 Experiment description of studies that identified Rab1b in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rab1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rab1b is involved
No pathways found





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