Gene description for PML
Gene name promyelocytic leukemia
Gene symbol PML
Other names/aliases -
Species Bos taurus
 Database cross references - PML
ExoCarta ExoCarta_100138545
Vesiclepedia VP_100138545
Entrez Gene 100138545
 PML identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PML
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IEA
    PML body organization GO:0030578 IEA
    positive regulation of DNA-templated transcription GO:0045893 IEA
Subcellular Localization
    chromatin GO:0000785 IEA
    nucleoplasm GO:0005654 IEA
    PML body GO:0016605 IEA
 Experiment description of studies that identified PML in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PML
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PML is involved
No pathways found





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