Gene description for Rnh1
Gene name ribonuclease/angiogenin inhibitor 1
Gene symbol Rnh1
Other names/aliases Rnh
Species Rattus norvegicus
 Database cross references - Rnh1
ExoCarta ExoCarta_100360501
Vesiclepedia VP_100360501
Entrez Gene 100360501
UniProt P29315  
 Rnh1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Rnh1
Molecular Function
    ribonuclease inhibitor activity GO:0008428 IBA
    ribonuclease inhibitor activity GO:0008428 IEA
    ribonuclease inhibitor activity GO:0008428 ISO
    ribonuclease inhibitor activity GO:0008428 ISS
Biological Process
    cell migration GO:0016477 IBA
    regulation of Arp2/3 complex-mediated actin nucleation GO:0034315 IBA
    tRNA stabilization GO:0036416 ISO
    regulation of angiogenesis GO:0045765 IBA
    regulation of angiogenesis GO:0045765 IEA
    regulation of angiogenesis GO:0045765 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 IBA
    lamellipodium GO:0030027 IBA
    angiogenin-PRI complex GO:0032311 IBA
    angiogenin-PRI complex GO:0032311 IEA
    angiogenin-PRI complex GO:0032311 ISO
 Experiment description of studies that identified Rnh1 in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rnh1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rnh1 is involved
No pathways found





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