Gene description for Snrpa1
Gene name small nuclear ribonucleoprotein polypeptide A'
Gene symbol Snrpa1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Snrpa1
ExoCarta ExoCarta_100361269
Vesiclepedia VP_100361269
Entrez Gene 100361269
 Snrpa1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Snrpa1
Molecular Function
    U2 snRNA binding GO:0030620 IBA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splicing, via spliceosome GO:0000398 ISO
    spermatogenesis GO:0007283 ISO
    biological_process GO:0008150 ND
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    spliceosomal complex GO:0005681 ISO
    U2-type spliceosomal complex GO:0005684 ISO
    U2 snRNP GO:0005686 IBA
    membrane GO:0016020 IEA
    nuclear body GO:0016604 ISO
    nuclear speck GO:0016607 IEA
    nuclear speck GO:0016607 ISO
    U2-type precatalytic spliceosome GO:0071005 ISO
    U2-type catalytic step 2 spliceosome GO:0071007 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
 Experiment description of studies that identified Snrpa1 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Snrpa1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Snrpa1 is involved
No pathways found





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