Gene description for TPBGL
Gene name trophoblast glycoprotein-like
Gene symbol TPBGL
Other names/aliases -
Species Homo sapiens
 Database cross references - TPBGL
ExoCarta ExoCarta_100507050
Vesiclepedia VP_100507050
Entrez Gene 100507050
HGNC 44159
UniProt P0DKB5  
 TPBGL identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for TPBGL
Biological Process
    negative regulation of canonical Wnt signaling pathway GO:0090090 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified TPBGL in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for TPBGL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TPBGL is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here