Gene description for Psph
Gene name phosphoserine phosphatase
Gene symbol Psph
Other names/aliases AI480570
PSP
PSPase
Species Mus musculus
 Database cross references - Psph
ExoCarta ExoCarta_100678
Entrez Gene 100678
UniProt Q99LS3  
 Psph identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Psph
Molecular Function
    phosphoserine phosphatase activity GO:0004647 ISO
    metal ion binding GO:0046872 IEA
    hydrolase activity GO:0016787 IEA
    magnesium ion binding GO:0000287 ISO
    protein homodimerization activity GO:0042803 ISO
    phosphatase activity GO:0016791 IEA
    calcium ion binding GO:0005509 ISO
Biological Process
    cellular amino acid biosynthetic process GO:0008652 IEA
    dephosphorylation GO:0016311 ISO
    L-serine metabolic process GO:0006563 ISO
    L-serine biosynthetic process GO:0006564 IBA
    metabolic process GO:0008152 IEA
Subcellular Localization
    neuron projection GO:0043005 ISO
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified Psph in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Psph
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psph is involved
PathwayEvidenceSource
Serine biosynthesis IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here