Gene description for Parp11
Gene name poly (ADP-ribose) polymerase family, member 11
Gene symbol Parp11
Other names/aliases 5330431N24Rik
AI851877
ARTD11
HIN1L
Species Mus musculus
 Database cross references - Parp11
ExoCarta ExoCarta_101187
Vesiclepedia VP_101187
Entrez Gene 101187
UniProt Q8CFF0  
 Parp11 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Parp11
Molecular Function
    NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 IBA
    NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 ISO
    nucleotidyltransferase activity GO:0016779 IEA
    NAD+-protein-cysteine ADP-ribosyltransferase activity GO:0140803 IEA
    NAD+-protein-lysine ADP-ribosyltransferase activity GO:0140804 IEA
    NAD+-protein-aspartate ADP-ribosyltransferase activity GO:0140806 IEA
    NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity GO:0140822 IEA
    NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity GO:0140844 IEA
    NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity GO:0140867 IEA
    NAD+-protein ADP-ribosyltransferase activity GO:1990404 IBA
    NAD+-protein ADP-ribosyltransferase activity GO:1990404 ISO
    NAD+-protein ADP-ribosyltransferase activity GO:1990404 ISS
Biological Process
    nuclear envelope organization GO:0006998 IMP
    spermatogenesis GO:0007283 IEA
    protein transport GO:0015031 IEA
    cell differentiation GO:0030154 IEA
    mRNA transport GO:0051028 IEA
    protein auto-ADP-ribosylation GO:0070213 ISO
    protein auto-ADP-ribosylation GO:0070213 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nuclear envelope GO:0005635 ISO
    nuclear pore GO:0005643 ISO
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    nuclear body GO:0016604 IEA
    nuclear body GO:0016604 ISO
 Experiment description of studies that identified Parp11 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Parp11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Parp11 is involved
No pathways found





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