Gene description for Ano1
Gene name	anoctamin 1, calcium activated chloride channel
Gene symbol	Ano1
Other names/aliases	Tmem16a
Species	Mus musculus
Database cross references - Ano1
ExoCarta	ExoCarta_101772
Vesiclepedia	VP_101772
Entrez Gene	101772
UniProt	Q8BHY3
Ano1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Ano1

Molecular Function     signaling receptor binding GO:0005102 ISO     calcium-activated cation channel activity GO:0005227 ISO     intracellularly calcium-gated chloride channel activity GO:0005229 IBA     intracellularly calcium-gated chloride channel activity GO:0005229 IDA     intracellularly calcium-gated chloride channel activity GO:0005229 ISO     voltage-gated chloride channel activity GO:0005247 IDA     chloride channel activity GO:0005254 IDA     chloride channel activity GO:0005254 IMP     chloride channel activity GO:0005254 ISO     protein binding GO:0005515 IPI     iodide transmembrane transporter activity GO:0015111 ISO     phospholipid scramblase activity GO:0017128 IDA     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 IDA     metal ion binding GO:0046872 IEA Biological Process     chloride transport GO:0006821 IDA     chloride transport GO:0006821 IDA     chloride transport GO:0006821 IMP     chloride transport GO:0006821 ISO     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IDA     iodide transport GO:0015705 ISO     cellular response to heat GO:0034605 IDA     positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 IMP     positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 ISO     regulation of membrane potential GO:0042391 IGI     regulation of membrane potential GO:0042391 IMP     detection of temperature stimulus involved in sensory perception of pain GO:0050965 IGI     detection of temperature stimulus involved in sensory perception of pain GO:0050965 IMP     detection of mechanical stimulus involved in sensory perception of pain GO:0050966 IMP     establishment of localization in cell GO:0051649 IDA     trachea development GO:0060438 IMP     mucus secretion GO:0070254 IMP     mucus secretion GO:0070254 ISO     protein localization to membrane GO:0072657 ISO     glial cell projection elongation GO:0106091 IMP     cellular response to peptide GO:1901653 ISO     chloride transmembrane transport GO:1902476 IBA     chloride transmembrane transport GO:1902476 IDA     chloride transmembrane transport GO:1902476 IMP     chloride transmembrane transport GO:1902476 ISO Subcellular Localization     nucleoplasm GO:0005654 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IDA     apical plasma membrane GO:0016324 IDA     apical plasma membrane GO:0016324 ISO     chloride channel complex GO:0034707 IEA     presynaptic membrane GO:0042734 IDA     cell projection GO:0042995 IEA     glutamatergic synapse GO:0098978 IDA