Gene description for Dnal1
Gene name dynein, axonemal, light chain 1
Gene symbol Dnal1
Other names/aliases 1700010H15Rik
AW121714
Dnalc1
E330027P08Rik
Species Mus musculus
 Database cross references - Dnal1
ExoCarta ExoCarta_105000
Vesiclepedia VP_105000
Entrez Gene 105000
UniProt Q05A62  
 Dnal1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dnal1
Molecular Function
    alpha-tubulin binding GO:0043014 IBA
    alpha-tubulin binding GO:0043014 IEA
    alpha-tubulin binding GO:0043014 ISO
    dynein heavy chain binding GO:0045504 IBA
    dynein heavy chain binding GO:0045504 IEA
    dynein heavy chain binding GO:0045504 ISO
Biological Process
    outer dynein arm assembly GO:0036158 IBA
    outer dynein arm assembly GO:0036158 IEA
    outer dynein arm assembly GO:0036158 ISO
Subcellular Localization
    cytoplasm GO:0005737 IBA
    microtubule GO:0005874 IEA
    outer dynein arm GO:0036157 ISA
 Experiment description of studies that identified Dnal1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dnal1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nphp4  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Dnal1 is involved
No pathways found





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