Gene description for Ano6
Gene name	anoctamin 6
Gene symbol	Ano6
Other names/aliases	2900059G15Rik AA407480 AW554778 F730003B03Rik Tmem16f
Species	Mus musculus
Database cross references - Ano6
ExoCarta	ExoCarta_105722
Entrez Gene	105722
UniProt	Q6P9J9
Ano6 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846

Gene ontology annotations for Ano6

Molecular Function     voltage-gated chloride channel activity GO:0005247 ISO     intracellular calcium activated chloride channel activity GO:0005229 IMP     calcium activated cation channel activity GO:0005227 ISO     protein homodimerization activity GO:0042803 IPI     phospholipid scramblase activity GO:0017128 IMP     chloride channel activity GO:0005254 IEA     voltage-gated ion channel activity GO:0005244 IDA Biological Process     ion transport GO:0006811 IEA     positive regulation of potassium ion export GO:1902304 ISO     purinergic nucleotide receptor signaling pathway GO:0035590 ISO     negative regulation of cell volume GO:0045794 ISO     bleb assembly GO:0032060 ISO     phospholipid transport GO:0015914 IMP     positive regulation of bone mineralization GO:0030501 ISO     phospholipid scrambling GO:0017121 ISO     positive regulation of endothelial cell apoptotic process GO:2000353 ISO     cation transport GO:0006812 ISO     phosphatidylserine exposure on blood platelet GO:0097045 ISO     calcium activated phosphatidylserine scrambling GO:0061589 IDA     calcium activated phospholipid scrambling GO:0061588 IMP     regulation of ion transmembrane transport GO:0034765 IDA     cation transmembrane transport GO:0098655 ISO     activation of blood coagulation via clotting cascade GO:0002543 ISO     transport GO:0006810 IEA     calcium activated galactosylceramide scrambling GO:0061591 IDA     bone mineralization involved in bone maturation GO:0035630 IMP     positive regulation of ion transmembrane transport GO:0034767 ISO     pore complex assembly GO:0046931 ISO     calcium activated phosphatidylcholine scrambling GO:0061590 IDA     calcium ion transmembrane transport GO:0070588 ISO     chloride transport GO:0006821 ISO     phosphatidylserine exposure on apoptotic cell surface GO:0070782 IMP     lipid transport GO:0006869 IEA     sodium ion transmembrane transport GO:0035725 ISO     chloride transmembrane transport GO:1902476 ISO     positive regulation of monocyte chemotaxis GO:0090026 ISO     blood coagulation GO:0007596 IMP     dendritic cell chemotaxis GO:0002407 IMP     regulation of anion transmembrane transport GO:1903959 ISO Subcellular Localization     plasma membrane GO:0005886 ISO     extracellular exosome GO:0070062 ISO     chloride channel complex GO:0034707 ISO     cell surface GO:0009986 ISO     intracellular GO:0005622 ISO     membrane GO:0016020 ISO     integral component of membrane GO:0016021 IEA