Gene description for Cggbp1
Gene name CGG triplet repeat binding protein 1
Gene symbol Cggbp1
Other names/aliases AA960172
AL023996
AW045841
Species Mus musculus
 Database cross references - Cggbp1
ExoCarta ExoCarta_106143
Vesiclepedia VP_106143
Entrez Gene 106143
UniProt Q8BHG9  
 Cggbp1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cggbp1
Molecular Function
    double-stranded DNA binding GO:0003690 ISO
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    DNA-binding transcription factor binding GO:0140297 IEA
    DNA-binding transcription factor binding GO:0140297 ISO
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    negative regulation of transcription by RNA polymerase II GO:0000122 ISO
    regulation of gene expression GO:0010468 IBA
    epigenetic regulation of gene expression GO:0040029 IEA
    epigenetic regulation of gene expression GO:0040029 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Cggbp1 in exosomes
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cggbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Otx2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Cggbp1 is involved
No pathways found





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