Gene description for Cggbp1
Gene name CGG triplet repeat binding protein 1
Gene symbol Cggbp1
Other names/aliases AA960172
AL023996
AW045841
Species Mus musculus
 Database cross references - Cggbp1
ExoCarta ExoCarta_106143
Entrez Gene 106143
UniProt Q8BHG9  
 Cggbp1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cggbp1
Molecular Function
    RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001227 ISO
    DNA binding GO:0003677 IEA
    RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 ISO
    double-stranded DNA binding GO:0003690 ISO
Biological Process
    transcription from RNA polymerase II promoter GO:0006366 ISO
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Cggbp1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cggbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cggbp1 is involved
No pathways found





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