Gene description for Mgat5
Gene name mannoside acetylglucosaminyltransferase 5
Gene symbol Mgat5
Other names/aliases 4930471A21Rik
5330407H02Rik
AI480971
GlcNAc-TV
Species Mus musculus
 Database cross references - Mgat5
ExoCarta ExoCarta_107895
Vesiclepedia VP_107895
Entrez Gene 107895
UniProt Q8R4G6  
 Mgat5 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Mgat5
Molecular Function
    protein phosphatase inhibitor activity GO:0004864 IEA
    protein phosphatase inhibitor activity GO:0004864 ISO
    acetylglucosaminyltransferase activity GO:0008375 IMP
    glycosyltransferase activity GO:0016757 IDA
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 IBA
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 IMP
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 ISO
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 ISS
    manganese ion binding GO:0030145 ISO
    manganese ion binding GO:0030145 ISS
Biological Process
    protein N-linked glycosylation GO:0006487 IBA
    protein N-linked glycosylation GO:0006487 IDA
    protein N-linked glycosylation GO:0006487 IMP
    protein N-linked glycosylation GO:0006487 ISO
    protein N-linked glycosylation via asparagine GO:0018279 ISO
    protein N-linked glycosylation via asparagine GO:0018279 ISS
    positive regulation of cell migration GO:0030335 IEA
    positive regulation of cell migration GO:0030335 ISO
    positive regulation of receptor signaling pathway via STAT GO:1904894 IEA
    positive regulation of receptor signaling pathway via STAT GO:1904894 ISO
Subcellular Localization
    Golgi membrane GO:0000139 ISS
    extracellular region GO:0005576 IEA
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IDA
    membrane GO:0016020 ISO
    perikaryon GO:0043204 IEA
 Experiment description of studies that identified Mgat5 in exosomes
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mgat5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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