Gene description for Mgat5
Gene name mannoside acetylglucosaminyltransferase 5
Gene symbol Mgat5
Other names/aliases 4930471A21Rik
5330407H02Rik
AI480971
GlcNAc-TV
Species Mus musculus
 Database cross references - Mgat5
ExoCarta ExoCarta_107895
Entrez Gene 107895
UniProt Q8R4G6  
 Mgat5 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Mgat5
Molecular Function
    acetylglucosaminyltransferase activity GO:0008375 IMP
    transferase activity GO:0016740 IEA
    transferase activity, transferring glycosyl groups GO:0016757 IEA
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 IMP
Biological Process
    protein N-linked glycosylation GO:0006487 IMP
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Mgat5 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mgat5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mgat5 is involved
PathwayEvidenceSource
N-Glycan antennae elongation IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here