Gene description for Mgat5
Gene name mannoside acetylglucosaminyltransferase 5
Gene symbol Mgat5
Other names/aliases 4930471A21Rik
Species Mus musculus
 Database cross references - Mgat5
ExoCarta ExoCarta_107895
Entrez Gene 107895
UniProt Q8R4G6  
 Mgat5 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Mgat5
Molecular Function
    acetylglucosaminyltransferase activity GO:0008375 IMP
    transferase activity GO:0016740 IEA
    transferase activity, transferring glycosyl groups GO:0016757 IEA
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity GO:0030144 IMP
Biological Process
    protein N-linked glycosylation GO:0006487 IMP
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Mgat5 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mgat5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mgat5 is involved
N-Glycan antennae elongation IEA Reactome

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