Gene description for Ltbp4
Gene name latent transforming growth factor beta binding protein 4
Gene symbol Ltbp4
Other names/aliases 2310046A13Rik
Species Mus musculus
 Database cross references - Ltbp4
ExoCarta ExoCarta_108075
Vesiclepedia VP_108075
Entrez Gene 108075
UniProt Q8K4G1  
 Ltbp4 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Ltbp4
Molecular Function
    extracellular matrix structural constituent GO:0005201 RCA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    transforming growth factor beta binding GO:0050431 IBA
    transforming growth factor beta binding GO:0050431 IEA
    transforming growth factor beta binding GO:0050431 ISO
Biological Process
    transforming growth factor beta receptor signaling pathway GO:0007179 IMP
    hormone secretion GO:0046879 IMP
    elastic fiber assembly GO:0048251 IMP
Subcellular Localization
    microfibril GO:0001527 IDA
    extracellular region GO:0005576 IEA
    extracellular matrix GO:0031012 IDA
    extracellular matrix GO:0031012 ISO
    extracellular matrix GO:0031012 ISS
    collagen-containing extracellular matrix GO:0062023 HDA
    collagen-containing extracellular matrix GO:0062023 IEA
    collagen-containing extracellular matrix GO:0062023 ISO
 Experiment description of studies that identified Ltbp4 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ltbp4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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