Gene description for Ints5
Gene name integrator complex subunit 5
Gene symbol Ints5
Other names/aliases 1110055N21Rik
mKIAA1698
Species Mus musculus
 Database cross references - Ints5
ExoCarta ExoCarta_109077
Vesiclepedia VP_109077
Entrez Gene 109077
UniProt Q8CHT3  
 Ints5 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ints5
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    snRNA processing GO:0016180 ISO
    snRNA processing GO:0016180 ISS
    snRNA 3'-end processing GO:0034472 IBA
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    nuclear membrane GO:0031965 IEA
    integrator complex GO:0032039 IBA
    integrator complex GO:0032039 ISO
    integrator complex GO:0032039 ISS
 Experiment description of studies that identified Ints5 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ints5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ints4  
Co-fractionation Mus musculus
2 Ints1  
Co-fractionation Mus musculus
3 Snx25  
Co-fractionation Mus musculus
4 Ints10  
Co-fractionation Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here