Gene description for Ints5
Gene name integrator complex subunit 5
Gene symbol Ints5
Other names/aliases 1110055N21Rik
mKIAA1698
Species Mus musculus
 Database cross references - Ints5
ExoCarta ExoCarta_109077
Entrez Gene 109077
UniProt Q8CHT3  
 Ints5 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ints5
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    snRNA processing GO:0016180 ISO
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    nucleus GO:0005634 ISO
    integrator complex GO:0032039 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Ints5 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ints5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ints5 is involved
No pathways found





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