Gene description for Clps
Gene name colipase, pancreatic
Gene symbol Clps
Other names/aliases 2200003J09Rik
Species Mus musculus
 Database cross references - Clps
ExoCarta ExoCarta_109791
Vesiclepedia VP_109791
Entrez Gene 109791
UniProt Q9CQC2  
 Clps identified in exosomes derived from the following tissue/cell type
Faeces 33431899    
Faeces 33431899    
 Gene ontology annotations for Clps
Molecular Function
    enzyme activator activity GO:0008047 ISO
Biological Process
    positive regulation of catalytic activity GO:0043085 ISO
    digestion GO:0007586 IEA
    lipid catabolic process GO:0016042 IEA
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Clps in exosomes
1
Experiment ID 303
MISEV standards
EM
EV Biophysical techniques
Cd63|Cd81|Cd9
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
2
Experiment ID 304
MISEV standards
EM
EV Biophysical techniques
Cd63|Cd81|Cd9
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
 Protein-protein interactions for Clps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Clps is involved
PathwayEvidenceSource
Digestion of dietary lipid IEA Reactome
Retinoid metabolism and transport IEA Reactome





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