Gene description for Rap1a
Gene name	RAS-related protein-1a
Gene symbol	Rap1a
Other names/aliases	AI848598 G-22K Krev-1 Rap1
Species	Mus musculus
Database cross references - Rap1a
ExoCarta	ExoCarta_109905
Entrez Gene	109905
UniProt	P62835
Rap1a identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	17486113
Oligodendrocytes	21136642
Pancreatic cells	19351151

Gene ontology annotations for Rap1a

Molecular Function     GTPase activity GO:0003924 IDA     Rap guanyl-nucleotide exchange factor activity GO:0017034 ISO     Ras GTPase binding GO:0017016 IPI     GTP binding GO:0005525 IEA     protein binding GO:0005515 IPI     protein complex binding GO:0032403 ISO     protein transporter activity GO:0008565 ISO     nucleotide binding GO:0000166 IEA Biological Process     nervous system development GO:0007399 IEA     nerve growth factor signaling pathway GO:0038180 ISO     positive regulation of neuron projection development GO:0010976 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     establishment of endothelial barrier GO:0061028 ISO     cellular response to nerve growth factor stimulus GO:1990090 ISO     regulation of cell junction assembly GO:1901888 ISO     cellular response to cAMP GO:0071320 ISO     positive regulation of GTPase activity GO:0043547 ISO     signal transduction GO:0007165 IEA     negative regulation of synaptic vesicle exocytosis GO:2000301 IGI     small GTPase mediated signal transduction GO:0007264 IDA     positive regulation of protein kinase activity GO:0045860 ISO     protein transport GO:0015031 ISO     Rap protein signal transduction GO:0032486 ISO     positive regulation of vasculogenesis GO:2001214 IMP Subcellular Localization     early endosome GO:0005769 ISO     late endosome GO:0005770 ISO     cytoplasm GO:0005737 ISO     neuron projection GO:0043005 IDA     guanyl-nucleotide exchange factor complex GO:0032045 IDA     myelin sheath GO:0043209 IDA     endosome GO:0005768 IEA     membrane GO:0016020 IEA     plasma membrane GO:0005886 IDA     perinuclear region of cytoplasm GO:0048471 ISO     cell junction GO:0030054 IDA     extracellular exosome GO:0070062 ISO