Gene description for SLC27A5
Gene name solute carrier family 27 (fatty acid transporter), member 5
Gene symbol SLC27A5
Other names/aliases ACSB
ACSVL6
BACS
BAL
FACVL3
FATP-5
FATP5
VLACSR
VLCS-H2
VLCSH2
Species Homo sapiens
 Database cross references - SLC27A5
ExoCarta ExoCarta_10998
Vesiclepedia VP_10998
Entrez Gene 10998
HGNC 10999
MIM 603314
UniProt Q9Y2P5  
 SLC27A5 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC27A5
Molecular Function
    protein complex binding GO:0032403 IEA
    long-chain fatty acid-CoA ligase activity GO:0004467 IEA
    cholate-CoA ligase activity GO:0047747 IEA
    fatty acid transporter activity GO:0015245 IEA
    ATP binding GO:0005524 IEA
    very long-chain fatty acid-CoA ligase activity GO:0031957 IDA
Biological Process
    bile acid biosynthetic process GO:0006699 TAS
    plasma membrane long-chain fatty acid transport GO:0015911 IEA
    ketone body biosynthetic process GO:0046951 IEA
    long-chain fatty acid metabolic process GO:0001676 IEA
    small molecule metabolic process GO:0044281 TAS
    bile acid and bile salt transport GO:0015721 TAS
    bile acid metabolic process GO:0008206 TAS
    very long-chain fatty acid metabolic process GO:0000038 IDA
    triglyceride mobilization GO:0006642 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 TAS
    integral component of endoplasmic reticulum membrane GO:0030176 IDA
    endoplasmic reticulum GO:0005783 IDA
    protein complex GO:0043234 IEA
    basal plasma membrane GO:0009925 IEA
 Experiment description of studies that identified SLC27A5 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC27A5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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