Gene description for Hdlbp
Gene name high density lipoprotein (HDL) binding protein
Gene symbol Hdlbp
Other names/aliases 1110005P14Rik
AA960365
AI118566
D1Ertd101e
Species Mus musculus
 Database cross references - Hdlbp
ExoCarta ExoCarta_110611
Vesiclepedia VP_110611
Entrez Gene 110611
UniProt Q8VDJ3  
 Hdlbp identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Hdlbp
Molecular Function
    RNA binding GO:0003723 IEA
    mRNA binding GO:0003729 IBA
Biological Process
    lipid transport GO:0006869 IEA
    cholesterol metabolic process GO:0008203 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
    high-density lipoprotein particle GO:0034364 IEA
 Experiment description of studies that identified Hdlbp in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Hdlbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Eed  
Affinity Capture-MS Mus musculus
2 Ubc  
Reconstituted Complex Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
4 Atxn1  
Affinity Capture-MS Mus musculus
5 Cbx5  
Co-fractionation Mus musculus
6 Atg16l1  
Affinity Capture-MS Mus musculus
7 Arhgap1 228359
Co-fractionation Mus musculus
8 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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