Gene description for Cds2
Gene name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
Gene symbol Cds2
Other names/aliases 5730450N06Rik
5730460C18Rik
AI854580
D2Wsu127e
Species Mus musculus
 Database cross references - Cds2
ExoCarta ExoCarta_110911
Entrez Gene 110911
UniProt Q99L43  
 Cds2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cds2
Molecular Function
    phosphatidate cytidylyltransferase activity GO:0004605 NAS
    transferase activity GO:0016740 IEA
    nucleotidyltransferase activity GO:0016779 IEA
    transferase activity, transferring phosphorus-containing groups GO:0016772 IEA
Biological Process
    phospholipid biosynthetic process GO:0008654 IEA
    glycosylation GO:0070085 NAS
    phototransduction GO:0007602 TAS
    CDP-diacylglycerol biosynthetic process GO:0016024 IBA
    phosphatidylglycerol biosynthetic process GO:0006655 IBA
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    membrane GO:0016020 ISO
    endoplasmic reticulum GO:0005783 NAS
    endoplasmic reticulum membrane GO:0005789 IBA
    mitochondrial inner membrane GO:0005743 IEA
    integral component of membrane GO:0016021 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified Cds2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cds2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cds2 is involved
PathwayEvidenceSource
Synthesis of PG IEA Reactome





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