Gene description for Cds2
Gene name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
Gene symbol Cds2
Other names/aliases 5730450N06Rik
5730460C18Rik
AI854580
D2Wsu127e
Species Mus musculus
 Database cross references - Cds2
ExoCarta ExoCarta_110911
Vesiclepedia VP_110911
Entrez Gene 110911
UniProt Q99L43  
 Cds2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cds2
Molecular Function
    phosphatidate cytidylyltransferase activity GO:0004605 ISO
    phosphatidate cytidylyltransferase activity GO:0004605 ISS
    phosphatidate cytidylyltransferase activity GO:0004605 NAS
Biological Process
    phototransduction GO:0007602 TAS
    CDP-diacylglycerol biosynthetic process GO:0016024 IEA
    CDP-diacylglycerol biosynthetic process GO:0016024 ISO
    CDP-diacylglycerol biosynthetic process GO:0016024 ISS
    glycosylation GO:0070085 NAS
    lipid droplet formation GO:0140042 IMP
    lipid droplet formation GO:0140042 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum GO:0005783 NAS
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 ISO
    membrane GO:0016020 ISS
 Experiment description of studies that identified Cds2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cds2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mapt  
Affinity Capture-MS Mus musculus
2 Fancd2  
Affinity Capture-MS Mus musculus
3 Lnx2  
Affinity Capture-MS Mus musculus
4 Sstr3  
Proximity Label-MS Mus musculus
View the network image/svg+xml



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