Gene description for D1Pas1
Gene name DNA segment, Chr 1, Pasteur Institute 1
Gene symbol D1Pas1
Other names/aliases Pl10
Species Mus musculus
 Database cross references - D1Pas1
ExoCarta ExoCarta_110957
Vesiclepedia VP_110957
Entrez Gene 110957
UniProt P16381  
 D1Pas1 identified in exosomes derived from the following tissue/cell type
Macrophages 23658846    
Macrophages 23658846    
Macrophages 23658846    
 Gene ontology annotations for D1Pas1
Molecular Function
    ATP-dependent RNA helicase activity GO:0004004 IBA
    DNA binding GO:0003677 IEA
    nucleic acid binding GO:0003676 IEA
    RNA binding GO:0003723 IEA
    nucleotide binding GO:0000166 IEA
    helicase activity GO:0004386 IEA
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
Biological Process
    RNA secondary structure unwinding GO:0010501 IBA
    cell differentiation GO:0030154 IEA
    chromosome segregation GO:0007059 IBA
    spermatogenesis GO:0007283 IEA
    multicellular organismal development GO:0007275 IEA
    regulation of gene expression GO:0010468 IBA
    translational initiation GO:0006413 IBA
Subcellular Localization
    cytoplasmic ribonucleoprotein granule GO:0036464 IBA
 Experiment description of studies that identified D1Pas1 in exosomes
1
Experiment ID 214
MISEV standards
EM
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Leishmania-infected-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 215
MISEV standards
EM
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name LPS-treated-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 216
MISEV standards
EM
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Normal-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for D1Pas1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which D1Pas1 is involved
No pathways found





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