Gene description for PADI2
Gene name	peptidyl arginine deiminase, type II
Gene symbol	PADI2
Other names/aliases	PAD-H19 PAD2 PDI2
Species	Homo sapiens
Database cross references - PADI2
ExoCarta	ExoCarta_11240
Vesiclepedia	VP_11240
Entrez Gene	11240
HGNC	18341
MIM	607935
UniProt	Q9Y2J8
PADI2 identified in sEVs derived from the following tissue/cell type
Thymus	23844026
Urine	19056867

Gene ontology annotations for PADI2

Molecular Function     protein-arginine deiminase activity GO:0004668 IDA     calcium ion binding GO:0005509 IEA     nuclear estrogen receptor binding GO:0030331 IPI     protein homodimerization activity GO:0042803 IDA     histone arginine deiminase activity GO:0140794 IBA     histone H3R2 arginine deiminase activity GO:0140795 IEA     histone H3R8 arginine deiminase activity GO:0140796 IEA     histone H3R17 arginine deiminase activity GO:0140797 IEA     histone H3R26 arginine deiminase activity GO:0140798 IDA     histone H4R3 arginine deiminase activity GO:0140809 IEA     histone H1R54 arginine deiminase activity GO:0140810 IEA     histone H2AR3 arginine deiminase activity GO:0140811 IEA Biological Process     chromatin remodeling GO:0006338 IBA     substantia nigra development GO:0021762 HEP     estrogen receptor signaling pathway GO:0030520 IMP     transcription initiation-coupled chromatin remodeling GO:0045815 IMP     negative regulation of chemokine-mediated signaling pathway GO:0070100 IDA     negative regulation of lymphocyte chemotaxis GO:1901624 IDA     cellular response to leukemia inhibitory factor GO:1990830 IEA Subcellular Localization     euchromatin GO:0000791 IDA     extracellular region GO:0005576 TAS     nucleus GO:0005634 IBA     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     azurophil granule lumen GO:0035578 TAS     extracellular exosome GO:0070062 HDA