Gene description for ERI2
Gene name ERI1 exoribonuclease family member 2
Gene symbol ERI2
Other names/aliases EXOD1
Species Homo sapiens
 Database cross references - ERI2
ExoCarta ExoCarta_112479
Entrez Gene 112479
HGNC 30541
UniProt A8K979  
 ERI2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ERI2
Molecular Function
    3'-5'-exoribonuclease activity GO:0000175 IBA
    nucleic acid binding GO:0003676 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    DNA catabolic process, exonucleolytic GO:0000738 IBA
    exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000467 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    nucleolus GO:0005730 IBA
 Experiment description of studies that identified ERI2 in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ERI2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ERI2 is involved
No pathways found

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