Gene description for Pzp
Gene name pregnancy zone protein
Gene symbol Pzp
Other names/aliases A1m
Species Mus musculus
 Database cross references - Pzp
ExoCarta ExoCarta_11287
Entrez Gene 11287
UniProt Q61838  
 Pzp identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Pzp
Molecular Function
    protein complex binding GO:0032403 ISO
    endopeptidase inhibitor activity GO:0004866 IDA
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    peptidase inhibitor activity GO:0030414 IEA
Biological Process
    embryo implantation GO:0007566 IGI
    negative regulation of endopeptidase activity GO:0010951 IDA
    negative regulation of peptidase activity GO:0010466 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    extracellular region GO:0005576 TAS
 Experiment description of studies that identified Pzp in exosomes
Experiment ID 39
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Pzp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pzp is involved
No pathways found

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