Gene description for Ces1d
Gene name carboxylesterase 1D
Gene symbol Ces1d
Other names/aliases Ces3
Species Rattus norvegicus
 Database cross references - Ces1d
ExoCarta ExoCarta_113902
Vesiclepedia VP_113902
Entrez Gene 113902
UniProt P16303  
 Ces1d identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Ces1d
Molecular Function
    sterol ester esterase activity GO:0004771 ISO
    sterol ester esterase activity GO:0004771 ISS
    triacylglycerol lipase activity GO:0004806 ISO
    triacylglycerol lipase activity GO:0004806 ISS
    fatty-acyl-ethyl-ester synthase activity GO:0030339 IEA
    all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity GO:0047376 IEA
    retinyl-palmitate esterase activity GO:0050253 IDA
    carboxylic ester hydrolase activity GO:0052689 IBA
    carboxylic ester hydrolase activity GO:0052689 IEA
    carboxylic ester hydrolase activity GO:0052689 ISO
    carboxylesterase activity GO:0106435 ISO
Biological Process
    retinoid metabolic process GO:0001523 TAS
    cholesterol biosynthetic process GO:0006695 ISO
    cholesterol metabolic process GO:0008203 ISO
    positive regulation of cholesterol efflux GO:0010875 ISO
    negative regulation of cholesterol storage GO:0010887 ISO
    lipid catabolic process GO:0016042 IBA
    lipid catabolic process GO:0016042 ISO
    short-chain fatty acid catabolic process GO:0019626 ISO
    epithelial cell differentiation GO:0030855 ISO
    very-low-density lipoprotein particle assembly GO:0034379 ISO
    retinol metabolic process GO:0042572 IEA
    cholesterol homeostasis GO:0042632 ISO
    reverse cholesterol transport GO:0043691 ISO
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
    acylglycerol catabolic process GO:0046464 ISO
    acylglycerol catabolic process GO:0046464 ISS
    medium-chain fatty acid metabolic process GO:0051791 ISO
    circadian temperature homeostasis GO:0060086 ISO
    cytosolic lipolysis GO:0061725 ISO
    cellular response to cold GO:0070417 ISO
    regulation of bile acid biosynthetic process GO:0070857 ISO
    cellular response to cholesterol GO:0071397 ISO
    cellular response to low-density lipoprotein particle stimulus GO:0071404 ISO
    positive regulation of cholesterol metabolic process GO:0090205 ISO
    cold-induced thermogenesis GO:0106106 ISO
    regulation of bile acid secretion GO:0120188 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum lumen GO:0005788 IEA
    endoplasmic reticulum lumen GO:0005788 ISO
    endoplasmic reticulum lumen GO:0005788 ISS
    lipid droplet GO:0005811 IBA
    lipid droplet GO:0005811 ISO
    lipid droplet GO:0005811 ISS
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified Ces1d in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ces1d
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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