Gene description for Hadh
Gene name hydroxyacyl-CoA dehydrogenase
Gene symbol Hadh
Other names/aliases Hadhsc
Species Rattus norvegicus
 Database cross references - Hadh
ExoCarta ExoCarta_113965
Entrez Gene 113965
UniProt Q9WVK7  
 Hadh identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Hadh
Molecular Function
    3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 ISO
    NAD+ binding GO:0070403 IEA
Biological Process
    response to activity GO:0014823 IDA
    response to drug GO:0042493 IDA
    fatty acid beta-oxidation GO:0006635 IMP
    response to hormone GO:0009725 IEP
    oxidation-reduction process GO:0055114 ISO
    negative regulation of insulin secretion GO:0046676 IMP
    response to insulin GO:0032868 IEP
Subcellular Localization
    mitochondrial matrix GO:0005759 IEA
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 ISO
    nucleoplasm GO:0005654 ISO
    mitochondrial inner membrane GO:0005743 ISO
 Experiment description of studies that identified Hadh in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Hadh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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