Gene description for Ugt1a6
Gene name UDP glucuronosyltransferase 1 family, polypeptide A6
Gene symbol Ugt1a6
Other names/aliases UDPGT 1-6
Udpgt
Ugt1
Ugt1a7
Species Rattus norvegicus
 Database cross references - Ugt1a6
ExoCarta ExoCarta_113992
Entrez Gene 113992
UniProt P08430  
 Ugt1a6 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Ugt1a6
Molecular Function
    glucuronosyltransferase activity GO:0015020 IDA
    protein complex binding GO:0032403 IDA
Biological Process
    flavonoid glucuronidation GO:0052696 IBA
    4-chlorobiphenyl metabolic process GO:0018880 IDA
    response to organic cyclic compound GO:0014070 IEP
    cellular response to hormone stimulus GO:0032870 IEP
    liver development GO:0001889 IEP
    cellular response to glucocorticoid stimulus GO:0071385 IDA
    xenobiotic glucuronidation GO:0052697 IBA
    response to lipopolysaccharide GO:0032496 IEP
    response to peptide hormone GO:0043434 IEP
    flavonoid biosynthetic process GO:0009813 IBA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    endoplasmic reticulum membrane GO:0005789 IBA
    protein complex GO:0043234 IDA
 Experiment description of studies that identified Ugt1a6 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugt1a6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ugt1a6 is involved
No pathways found





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