Gene description for Banf1
Gene name barrier to autointegration factor 1
Gene symbol Banf1
Other names/aliases Baf
Bcrp1
L2bp1
L2bp1/Baf
Species Rattus norvegicus
 Database cross references - Banf1
ExoCarta ExoCarta_114087
Vesiclepedia VP_114087
Entrez Gene 114087
UniProt Q9R1T1  
 Banf1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Banf1
Molecular Function
    DNA binding GO:0003677 IBA
    DNA binding GO:0003677 ISO
    double-stranded DNA binding GO:0003690 ISO
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    identical protein binding GO:0042802 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    chromatin organization GO:0006325 ISO
    chromatin organization GO:0006325 ISS
    response to oxidative stress GO:0006979 ISO
    response to oxidative stress GO:0006979 ISS
    mitotic nuclear membrane reassembly GO:0007084 ISO
    mitotic nuclear membrane reassembly GO:0007084 ISS
    biological_process GO:0008150 ND
    DNA integration GO:0015074 ISO
    negative regulation of type I interferon production GO:0032480 ISO
    negative regulation of type I interferon production GO:0032480 ISS
    negative regulation of viral genome replication GO:0045071 ISO
    negative regulation of innate immune response GO:0045824 ISO
    chromosome organization GO:0051276 IBA
    negative regulation of cGAS/STING signaling pathway GO:0160049 ISO
Subcellular Localization
    chromatin GO:0000785 ISO
    chromatin GO:0000785 ISS
    condensed chromosome GO:0000793 IBA
    condensed chromosome GO:0000793 IDA
    condensed chromosome GO:0000793 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nuclear envelope GO:0005635 IEA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Banf1 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Banf1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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