Gene description for Sardh
Gene name sarcosine dehydrogenase
Gene symbol Sardh
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Sardh
ExoCarta ExoCarta_114123
Vesiclepedia VP_114123
Entrez Gene 114123
UniProt Q64380  
 Sardh identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Sardh
Molecular Function
    folic acid binding GO:0005542 IDA
    sarcosine dehydrogenase activity GO:0008480 IBA
    sarcosine dehydrogenase activity GO:0008480 IDA
    sarcosine dehydrogenase activity GO:0008480 TAS
    oxidoreductase activity GO:0016491 NAS
    flavin adenine dinucleotide binding GO:0050660 IDA
Biological Process
    glycine biosynthetic process GO:0006545 TAS
    tetrahydrofolate interconversion GO:0035999 IDA
    choline catabolic process GO:0042426 NAS
    choline catabolic process GO:0042426 TAS
    sarcosine catabolic process GO:1901053 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    mitochondrial matrix GO:0005759 IBA
    mitochondrial matrix GO:0005759 IDA
 Experiment description of studies that identified Sardh in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Sardh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sardh is involved
PathwayEvidenceSource
Choline catabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome





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