Gene description for Actg2
Gene name actin, gamma 2, smooth muscle, enteric
Gene symbol Actg2
Other names/aliases ACTA3
Act-4
Act4
SMGA
Species Mus musculus
 Database cross references - Actg2
ExoCarta ExoCarta_11468
Entrez Gene 11468
UniProt P63268  
 Actg2 identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Actg2
Molecular Function
    nucleotide binding GO:0000166 IEA
    ATP binding GO:0005524 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    blood microparticle GO:0072562 ISO
    cell periphery GO:0071944 IDA
    extracellular space GO:0005615 ISO
    cytoskeleton GO:0005856 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Actg2 in exosomes
1
Experiment ID 39
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|HSC70
EV Cytosolic markers
✔
FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Actg2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Actg2 is involved
PathwayEvidenceSource
Smooth Muscle Contraction IEA Reactome





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