Gene description for Avil
Gene name advillin
Gene symbol Avil
Other names/aliases Advil
DOC6
Species Mus musculus
 Database cross references - Avil
ExoCarta ExoCarta_11567
Entrez Gene 11567
UniProt O88398  
 Avil identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Avil
Molecular Function
    actin binding GO:0003779 ISO
    protein binding GO:0005515 IPI
Biological Process
    cilium morphogenesis GO:0060271 ISO
    regulation of neuron projection development GO:0010975 IEA
    actin filament organization GO:0007015 ISS
    actin filament capping GO:0051693 IEA
    positive regulation of neuron projection development GO:0010976 ISO
    cytoskeleton organization GO:0007010 IEA
    nervous system development GO:0007399 ISO
Subcellular Localization
    neuron projection GO:0043005 ISO
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
    cell projection GO:0042995 ISO
 Experiment description of studies that identified Avil in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Avil
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Avil is involved
No pathways found





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