Gene description for Aebp1
Gene name AE binding protein 1
Gene symbol Aebp1
Other names/aliases ACLP
Species Mus musculus
 Database cross references - Aebp1
ExoCarta ExoCarta_11568
Entrez Gene 11568
UniProt Q640N1  
 Aebp1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Aebp1
Molecular Function
    metallocarboxypeptidase activity GO:0004181 IEA
    calmodulin binding GO:0005516 IEA
    transcription corepressor activity GO:0003714 IDA
    zinc ion binding GO:0008270 IEA
    RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001227 ISO
    RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 ISO
    carboxypeptidase activity GO:0004180 IDA
    DNA binding GO:0003677 IEA
Biological Process
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    regulation of transcription, DNA-templated GO:0006355 IDA
    negative regulation of nucleic acid-templated transcription GO:1903507 IDA
    transcription, DNA-templated GO:0006351 IEA
    proteolysis GO:0006508 IDA
    transcription from RNA polymerase II promoter GO:0006366 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IEA
    extracellular matrix GO:0031012 ISO
    extracellular region GO:0005576 IEA
    nucleus GO:0005634 IEA
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Aebp1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aebp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aebp1 is involved
No pathways found

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