Gene description for Aebp2
Gene name AE binding protein 2
Gene symbol Aebp2
Other names/aliases AU023766
B230313N05Rik
Species Mus musculus
 Database cross references - Aebp2
ExoCarta ExoCarta_11569
Vesiclepedia VP_11569
Entrez Gene 11569
UniProt Q9Z248  
 Aebp2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Aebp2
Molecular Function
    DNA binding GO:0003677 IEA
    transcription coregulator activity GO:0003712 IDA
    transcription coregulator activity GO:0003712 IMP
    metal ion binding GO:0046872 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    chromatin organization GO:0006325 IEA
    regulation of DNA-templated transcription GO:0006355 IDA
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 ISO
    ESC/E(Z) complex GO:0035098 IBA
    ESC/E(Z) complex GO:0035098 IDA
    ESC/E(Z) complex GO:0035098 ISO
 Experiment description of studies that identified Aebp2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Aebp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Jarid2  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
2 Ezh1  
Affinity Capture-MS Mus musculus
3 Eed  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
4 Suz12  
Affinity Capture-MS Mus musculus
5 Ezh2  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
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