Gene description for Angpt1
Gene name	angiopoietin 1
Gene symbol	Angpt1
Other names/aliases	1110046O21Rik Ang-1 Ang1
Species	Mus musculus
Database cross references - Angpt1
ExoCarta	ExoCarta_11600
Entrez Gene	11600
UniProt	O08538
Angpt1 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Angpt1

Molecular Function     receptor tyrosine kinase binding GO:0030971 ISO     vascular endothelial growth factor receptor binding GO:0005172 TAS     receptor binding GO:0005102 IPI Biological Process     Tie signaling pathway GO:0048014 TAS     multicellular organismal development GO:0007275 IEA     negative regulation of protein import into nucleus GO:0042308 IDA     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 IDA     vasculogenesis GO:0001570 TAS     positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     positive regulation of endothelial cell migration GO:0010595 TAS     positive regulation of cell adhesion GO:0045785 IDA     cell-substrate adhesion GO:0031589 IDA     protein homooligomerization GO:0051260 ISO     positive chemotaxis GO:0050918 ISO     in utero embryonic development GO:0001701 IMP     positive regulation of protein ubiquitination GO:0031398 ISO     positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 TAS     vasculogenesis involved in coronary vascular morphogenesis GO:0060979 TAS     negative regulation of protein phosphorylation GO:0001933 IDA     negative regulation of cytokine secretion involved in immune response GO:0002740 IDA     regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 IGI     positive regulation of blood vessel endothelial cell migration GO:0043536 ISO     negative regulation of apoptotic process GO:0043066 ISO     endoderm development GO:0007492 TAS     activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 ISO     regulation of tumor necrosis factor production GO:0032680 IDA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 IDA     negative regulation of cell adhesion GO:0007162 ISO     positive regulation of protein kinase B signaling GO:0051897 ISO     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO     cell differentiation GO:0030154 IEA     heparin biosynthetic process GO:0030210 ISO     patterning of blood vessels GO:0001569 TAS     endocardium morphogenesis GO:0003160 TAS     cardiac muscle tissue morphogenesis GO:0055008 TAS     negative regulation of neuron apoptotic process GO:0043524 IGI     ovarian follicle development GO:0001541 ISO     glomerulus vasculature development GO:0072012 ISO     angiogenesis GO:0001525 IMP     hemopoiesis GO:0030097 IDA     regulation of satellite cell proliferation GO:0014842 ISO     sprouting angiogenesis GO:0002040 ISO     positive regulation of receptor internalization GO:0002092 ISO     regulation of protein binding GO:0043393 IDA     regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 IDA     negative regulation of vascular permeability GO:0043116 ISO     negative regulation of endothelial cell apoptotic process GO:2000352 ISO     protein localization to cell surface GO:0034394 ISO Subcellular Localization     membrane raft GO:0045121 ISO     extracellular region GO:0005576 IEA     microvillus GO:0005902 ISO     plasma membrane GO:0005886 ISO     extracellular space GO:0005615 ISO     extracellular exosome GO:0070062 ISO