Gene description for F11r
Gene name F11 receptor
Gene symbol F11r
Other names/aliases Jam1
Species Rattus norvegicus
 Database cross references - F11r
ExoCarta ExoCarta_116479
Entrez Gene 116479
UniProt Q9JHY1  
 F11r identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Reticulocytes 21828046    
 Gene ontology annotations for F11r
Molecular Function
    PDZ domain binding GO:0030165 ISO
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of blood pressure GO:0045777 IDA
    epithelial cell differentiation GO:0030855 ISO
    response to radiation GO:0009314 IEP
    establishment of protein localization to plasma membrane GO:0090002 ISO
    negative regulation of GTPase activity GO:0034260 ISO
    cell differentiation GO:0030154 IEP
    regulation of actin cytoskeleton reorganization GO:2000249 ISO
    regulation of membrane permeability GO:0090559 ISO
    establishment of endothelial intestinal barrier GO:0090557 ISO
    viral process GO:0016032 IEA
    actomyosin structure organization GO:0031032 ISO
    positive regulation of GTPase activity GO:0043547 ISO
    intestinal absorption GO:0050892 ISO
    cell adhesion GO:0007155 ISO
Subcellular Localization
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
    cell junction GO:0030054 ISO
    integral component of membrane GO:0016021 IEA
    slit diaphragm GO:0036057 IDA
    cytoplasmic vesicle GO:0031410 IDA
    microtubule cytoskeleton GO:0015630 ISO
    bicellular tight junction GO:0005923 ISO
    cell-cell junction GO:0005911 IDA
 Experiment description of studies that identified F11r in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for F11r
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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