Gene description for Sacm1l
Gene name SAC1 suppressor of actin mutations 1-like (yeast)
Gene symbol Sacm1l
Other names/aliases Sac1
Species Rattus norvegicus
 Database cross references - Sacm1l
ExoCarta ExoCarta_116482
Vesiclepedia VP_116482
Entrez Gene 116482
UniProt Q9ES21  
 Sacm1l identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Sacm1l
Molecular Function
    phosphatidylinositol-3-phosphate phosphatase activity GO:0004438 IDA
    phosphatase activity GO:0016791 IEA
    phosphatase activity GO:0016791 IMP
    phosphatidylinositol-4-phosphate phosphatase activity GO:0043812 IBA
    phosphatidylinositol-4-phosphate phosphatase activity GO:0043812 IDA
    phosphatidylinositol-4-phosphate phosphatase activity GO:0043812 IEA
    phosphatidylinositol-4-phosphate phosphatase activity GO:0043812 ISO
    phosphatidylinositol-3,5-bisphosphate phosphatase activity GO:0106018 IDA
Biological Process
    phosphatidylinositol dephosphorylation GO:0046856 IBA
    phosphatidylinositol dephosphorylation GO:0046856 IEA
    phosphatidylinositol dephosphorylation GO:0046856 IMP
    phosphatidylinositol dephosphorylation GO:0046856 ISO
    exocytic insertion of neurotransmitter receptor to postsynaptic membrane GO:0098967 ISO
    neurotransmitter receptor transport to postsynaptic membrane GO:0098969 EXP
    neurotransmitter receptor transport to postsynaptic membrane GO:0098969 IDA
    neurotransmitter receptor transport to postsynaptic membrane GO:0098969 IEP
    neurotransmitter receptor transport to postsynaptic membrane GO:0098969 IMP
    vesicle-mediated transport in synapse GO:0099003 EXP
    vesicle-mediated transport in synapse GO:0099003 IDA
    vesicle-mediated transport in synapse GO:0099003 IEP
    vesicle-mediated transport in synapse GO:0099003 IMP
    vesicle-mediated transport in synapse GO:0099003 ISO
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    Golgi membrane GO:0000139 ISO
    Golgi membrane GO:0000139 ISS
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    endoplasmic reticulum membrane GO:0005789 ISO
    Golgi apparatus GO:0005794 ISO
    Golgi apparatus GO:0005794 ISS
    membrane GO:0016020 IEA
    AMPA glutamate receptor complex GO:0032281 ISO
    glutamatergic synapse GO:0098978 EXP
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
    glutamatergic synapse GO:0098978 ISO
    endoplasmic reticulum-plasma membrane contact site GO:0140268 IDA
    endoplasmic reticulum-plasma membrane contact site GO:0140268 IEA
    endoplasmic reticulum-plasma membrane contact site GO:0140268 ISO
 Experiment description of studies that identified Sacm1l in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Sacm1l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here