Gene description for Txn1
Gene name	thioredoxin 1
Gene symbol	Txn1
Other names/aliases	Txn
Species	Rattus norvegicus
Database cross references - Txn1
ExoCarta	ExoCarta_116484
Vesiclepedia	VP_116484
Entrez Gene	116484
UniProt	P11232
Txn1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Txn1

Molecular Function     thioredoxin-disulfide reductase (NADPH) activity GO:0004791 TAS     protein-disulfide reductase activity GO:0015035 ISO     enzyme binding GO:0019899 IPI     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     protein-disulfide reductase (NAD(P)H) activity GO:0047134 IEA     protein-disulfide reductase (NAD(P)H) activity GO:0047134 ISO Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IEA     negative regulation of transcription by RNA polymerase II GO:0000122 ISO     response to radiation GO:0009314 IEA     response to radiation GO:0009314 ISO     response to radiation GO:0009314 ISS     response to xenobiotic stimulus GO:0009410 IEP     response to selenium ion GO:0010269 IEP     response to activity GO:0014823 IEP     positive regulation of peptidyl-serine phosphorylation GO:0033138 ISO     cell redox homeostasis GO:0045454 IEA     cell redox homeostasis GO:0045454 ISO     cell redox homeostasis GO:0045454 ISO     negative regulation of protein export from nucleus GO:0046826 IEA     negative regulation of protein export from nucleus GO:0046826 ISO     response to axon injury GO:0048678 IEP     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IEA     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 ISO     cellular detoxification of hydrogen peroxide GO:0061692 IEA     cellular detoxification of hydrogen peroxide GO:0061692 ISO     cellular response to antibiotic GO:0071236 IEP     cellular response to glucose stimulus GO:0071333 IEP     cellular response to hyperoxia GO:0071455 IEP     cellular response to xenobiotic stimulus GO:0071466 IEP     response to dexamethasone GO:0071548 IEP     response to nitric oxide GO:0071731 IEA     response to nitric oxide GO:0071731 ISO     response to thyroxine GO:0097068 IEP     positive regulation of peptidyl-cysteine S-nitrosylation GO:2000170 IEA     positive regulation of peptidyl-cysteine S-nitrosylation GO:2000170 ISO Subcellular Localization     extracellular region GO:0005576 IEA     extracellular region GO:0005576 ISO     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     axon GO:0030424 IDA     dendrite GO:0030425 IDA     neuronal cell body GO:0043025 IDA