Gene description for Pip4k2a
Gene name phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Gene symbol Pip4k2a
Other names/aliases Pip5k2a
Species Rattus norvegicus
 Database cross references - Pip4k2a
ExoCarta ExoCarta_116723
Entrez Gene 116723
UniProt Q9R0I8  
 Pip4k2a identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Pip4k2a
Molecular Function
    ATP binding GO:0005524 IEA
    phosphatidylinositol phosphate kinase activity GO:0016307 IEA
    1-phosphatidylinositol-5-phosphate 4-kinase activity GO:0016309 IEA
Biological Process
    megakaryocyte development GO:0035855 ISO
    phosphatidylinositol phosphorylation GO:0046854 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Pip4k2a in exosomes
1
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Pip4k2a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pip4k2a is involved
No pathways found





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