Gene description for Akr1b3
Gene name	aldo-keto reductase family 1, member B3 (aldose reductase)
Gene symbol	Akr1b3
Other names/aliases	ALR2 AR Ahr-1 Ahr1 Akr1b1 Aldor1 Aldr1
Species	Mus musculus
Database cross references - Akr1b3
ExoCarta	ExoCarta_11677
Entrez Gene	11677
UniProt	P45376
Akr1b3 identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts	18494037
Mast cells	17486113
Pancreatic cells	19351151

Gene ontology annotations for Akr1b3

Molecular Function     glyceraldehyde oxidoreductase activity GO:0043795 ISO     oxidoreductase activity GO:0016491 IEA     alditol:NADP+ 1-oxidoreductase activity GO:0004032 ISO Biological Process     daunorubicin metabolic process GO:0044597 ISO     positive regulation of smooth muscle cell proliferation GO:0048661 ISO     cellular response to hydrogen peroxide GO:0070301 ISO     response to organic substance GO:0010033 ISO     response to water deprivation GO:0009414 ISO     oxidation-reduction process GO:0055114 ISO     inner medullary collecting duct development GO:0072061 ISO     tissue homeostasis GO:0001894 ISO     cellular response to methylglyoxal GO:0097238 ISO     sorbitol biosynthetic process GO:0006061 ISO     doxorubicin metabolic process GO:0044598 ISO     stress-activated protein kinase signaling cascade GO:0031098 ISO     monosaccharide metabolic process GO:0005996 ISO     norepinephrine metabolic process GO:0042415 ISO     naphthalene metabolic process GO:0018931 ISO     positive regulation of JAK-STAT cascade GO:0046427 ISO Subcellular Localization     cytosol GO:0005829 ISO     Schwann cell microvillus GO:0097454 ISO     paranodal junction GO:0033010 ISO     cytoplasm GO:0005737 ISO     nucleoplasm GO:0005654 ISO     extracellular exosome GO:0070062 ISO     mast cell granule GO:0042629 ISO     cell projection cytoplasm GO:0032838 ISO     Schmidt-Lanterman incisure GO:0043220 ISO     perinuclear region of cytoplasm GO:0048471 ISO     extracellular space GO:0005615 ISO