Gene description for Crym
Gene name crystallin, mu
Gene symbol Crym
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Crym
ExoCarta ExoCarta_117024
Entrez Gene 117024
UniProt Q9QYU4  
 Crym identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Crym
Molecular Function
    hormone binding GO:0042562 ISO
    thyroid hormone binding GO:0070324 ISO
    protein homodimerization activity GO:0042803 ISO
    thiomorpholine-carboxylate dehydrogenase activity GO:0047127 IEA
    transcription corepressor activity GO:0003714 ISO
    molecular_function GO:0003674 ND
    NADP binding GO:0050661 ISO
Biological Process
    response to vitamin D GO:0033280 IEP
    thyroid hormone metabolic process GO:0042403 ISO
    response to hormone GO:0009725 IEP
    mitochondrial transport GO:0006839 IDA
    oxidation-reduction process GO:0055114 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    thyroid hormone transport GO:0070327 ISO
    sensory perception of sound GO:0007605 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IDA
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Crym in exosomes
1
Experiment ID 192
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
CD63|CD81|FLOT
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Crym
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Crym is involved
No pathways found





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