Gene description for Hnrnpu
Gene name heterogeneous nuclear ribonucleoprotein U
Gene symbol Hnrnpu
Other names/aliases Hnrpu
SN1
Species Rattus norvegicus
 Database cross references - Hnrnpu
ExoCarta ExoCarta_117280
Entrez Gene 117280
 Hnrnpu identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Hnrnpu
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    core promoter binding GO:0001047 ISO
Biological Process
    circadian regulation of gene expression GO:0032922 ISO
    osteoblast differentiation GO:0001649 ISO
    CRD-mediated mRNA stabilization GO:0070934 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    membrane GO:0016020 ISO
    nucleoplasm GO:0005654 ISO
    CRD-mediated mRNA stability complex GO:0070937 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
    viral nucleocapsid GO:0019013 IEA
    cytoplasmic ribonucleoprotein granule GO:0036464 ISO
    ribonucleoprotein complex GO:0030529 ISO
 Experiment description of studies that identified Hnrnpu in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Hnrnpu
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpu is involved
No pathways found





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