Gene description for Slc4a7
Gene name solute carrier family 4, sodium bicarbonate cotransporter, member 7
Gene symbol Slc4a7
Other names/aliases NBC3
NBCn1
Species Rattus norvegicus
 Database cross references - Slc4a7
ExoCarta ExoCarta_117955
Entrez Gene 117955
UniProt Q9R1N3  
 Slc4a7 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc4a7
Molecular Function
    inorganic anion exchanger activity GO:0005452 IEA
    sodium:bicarbonate symporter activity GO:0008510 IBA
Biological Process
    retina vasculature morphogenesis in camera-type eye GO:0061299 ISO
    sodium ion transmembrane transport GO:0035725 IBA
    auditory receptor cell development GO:0060117 ISO
    visual perception GO:0007601 ISO
    retinal cell programmed cell death GO:0046666 ISO
    bicarbonate transport GO:0015701 IBA
    anion transmembrane transport GO:0098656 IEA
    camera-type eye photoreceptor cell differentiation GO:0060219 ISO
    regulation of intracellular pH GO:0051453 IBA
    cochlear nucleus development GO:0021747 ISO
Subcellular Localization
    cytoplasmic vesicle GO:0031410 IDA
    cytoplasm GO:0005737 ISO
    stereocilium GO:0032420 IDA
    basolateral plasma membrane GO:0016323 ISO
    apical plasma membrane GO:0016324 ISO
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
    integral component of plasma membrane GO:0005887 IBA
    synapse GO:0045202 IDA
 Experiment description of studies that identified Slc4a7 in exosomes
1
Experiment ID 94
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc4a7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc4a7 is involved
PathwayEvidenceSource
Bicarbonate transporters IEA Reactome





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