Gene description for Arf5
Gene name ADP-ribosylation factor 5
Gene symbol Arf5
Other names/aliases -
Species Mus musculus
 Database cross references - Arf5
ExoCarta ExoCarta_11844
Entrez Gene 11844
UniProt P84084  
 Arf5 identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
Pancreatic cells 19351151    
 Gene ontology annotations for Arf5
Molecular Function
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    GTP binding GO:0005525 TAS
Biological Process
    transport GO:0006810 IEA
    protein transport GO:0015031 TAS
    vesicle-mediated transport GO:0016192 IEA
    small GTPase mediated signal transduction GO:0007264 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    intracellular GO:0005622 IEA
    plasma membrane GO:0005886 IDA
    extracellular exosome GO:0070062 ISO
    Golgi apparatus GO:0005794 IEA
 Experiment description of studies that identified Arf5 in exosomes
1
Experiment ID 39
ISEV standards
IEM
EV Biophysical techniques
TSG101|HSC70
EV Cytosolic markers
FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
2
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Arf5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Arf5 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here